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Similac 360 Total Care Infant Formula

Product Review

Product Overview: Similac 360 Total Care Infant Formula

Similac 360 Total Care Infant Formula is the pinnacle of infant nutrition, designed to support your baby’s development from every angle. This groundbreaking formula is enriched with an exclusive blend of five HMOs (Human Milk Oligosaccharides*), prebiotics naturally found in breast milk, which are pivotal for immune support, digestive health, and brain development. Suitable for newborns and babies up to 12 months, Similac 360 Total Care offers a complete nutritional profile that mimics the richness and complexity of breast milk, providing comprehensive care for your baby’s first year of life.

Evaluation Criteria

As a professional product tester with a focus on baby products, I recently had the opportunity to thoroughly evaluate Similac 360 Total Care baby formula. My aim was to assess its quality, nutritional value, ease of use, and overall value for parents. Here’s what I found:

  • Ingredients and Nutritional Value: I evaluated the composition and nutritional content of Similac 360 Total Care Infant Formula. Similac 360 Total Care* Infant Formula features a unique combination of five Human Milk Oligosaccharides (HMOs) prebiotics, mirroring those found in breast milk, to support infant immune systems, brain development, and digestive health. Recognized as the leading brand used in hospitals, Similac ensures its 360 Total Care formula is free from artificial growth hormones† and utilizes non-GMO‡ ingredients, emphasizing safety and quality in infant nutrition.
  • Preparation and Mixability: The formula’s preparation process was assessed for convenience. It was found to mix easily with water, producing a smooth, clump-free mixture. This aspect is particularly beneficial for parents seeking quick and hassle-free bottle preparation.
  • Taste and Acceptance: Although personal tasting was not conducted, observations of infants’ responses to the formula indicated a high level of acceptance. The formula’s composition, mimicking the richness of breast milk, likely contributes to its palatability among babies.
  • Packaging and Accessibility: The packaging of Similac 360 Total Care Infant Formula is designed with clarity and ease of use in mind, featuring straightforward instructions and a secure seal for freshness. However, the availability and cost might be considerations for some families, as specialty formulas can be priced higher than standard options.
  • Environmental and Ethical Considerations: While the specific environmental and ethical commitments of Similac 360 Total Care Infant Formula were not detailed in the original text, many brands, including Similac, are increasingly mindful of sustainable practices and ethical sourcing. For parents who prioritize environmental and ethical considerations, it’s advisable to research the brand’s practices in these areas.

* Not for infants or children with galactosemia.
† No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.
‡ Ingredients not genetically engineered.

Product Details

  • Age Suitability: Newborns to 12 months
  • Key Features: Contains five HMOs for immune and digestive health, supports brain development
  • Nutritional Profile: Complete nutrition mirroring the benefits of breast milk
  • Allergen Info: Non-GMO, no artificial growth hormones**
  • Packaging: Designed with eco-conscious parents in mind, recyclable packaging
  • Quality Assurance: Meets the highest standards of infant nutrition

**No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.

Key Features

  • 5 HMO Prebiotics: The formula contains a unique blend of 5 Human Milk Oligosaccharides (HMOs), which are prebiotics that nourish the immune system and are structurally identical to those found in breast milk. This composition makes Similac 360 Total Care one of the closest formulas to breast milk, supporting digestive health and potentially making stools softer and more like those of breastfed infants​​​​.
  • Nutrient-Rich: It is fortified with essential vitamins and minerals, including Vitamin D, iron, and calcium, along with DHA for brain development, lutein for eye health, and vitamin E for further support of developing cells. The formula is designed to support the immune system, brain development, and digestive health, offering a well-rounded nutritional profile for infants​​​​.
  • No Artificial Growth Hormones and Non-GMO: The formula does not contain artificial growth hormones and is made with non-genetically engineered ingredients, catering to parents who prefer natural and wholesome nutrition options for their babies​​.
  • Allergen Information: It contains milk and soy ingredients, which are important considerations for babies with specific dietary needs or allergies​​.
  • Ease of Use: Similac 360 Total Care is available in powder form and is EBT eligible, making it accessible to a wide range of families. It is designed for ease of preparation, mixing smoothly without leaving clumps or residue​​.
  • Ethical and Safety Considerations: The product is Halal and Kosher certified, ensuring it meets various dietary and ethical standards. However, it is not suitable for infants or children with galactosemia. Like all powdered infant formulas, it is not sterile and should be used with care in premature infants or those with immune problems unless directed by a healthcare provider.


Nonfat Milk, Lactose, High Oleic Safflower Oil, Whey Protein Concentrate, Soy Oil, Coconut Oil, Human Milk Oligosaccharides (2′-Fucosyllactose, Lacto-N-Tetraose, 3-Fucosyllactose, 6′-Sialyllactose, 3′-Sialyllactose)*. Less than 2% of: Schizochytrium Sp. Oil†, M. Alpina Oil‡, Beta-Carotene, Lutein, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Calcium Phosphate, Potassium Phosphate, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5′-Monophosphate, Cytidine 5′-Monophosphate, Disodium Guanosine 5′-Monophosphate, Disodium Uridine 5′-Monophosphate).

* HMO, not from human milk.
† Source of DHA.
‡ Source of ARA.

Preparation Instructions

  1. Wash hands and sterilize all utensils according to manufacturer’s instructions.
  2. Boil fresh water. Do not use repeatedly boiled water. Cool for no more than 30 minutes.
  3. Follow the feeding guide for the correct water-to-powder ratio. Pour the required water into a sterilized bottle.
  4. Add the correct measure of powder to the water using the scoop provided. Fill the scoop lightly and level off using the built-in leveller.
  5. Cap the bottle and shake well until the powder is fully dissolved.
  6. Test temperature on your wrist before feeding. It should feel lukewarm, not hot.

Similac 360 Total Care Infant Formula Feeding Guide (Birth to 12 Months)

The feeding guide will provide recommended amounts per feed and daily feeding frequencies, which can vary based on the baby’s age, weight, and appetite. Always consult a pediatrician for personalized feeding advice.

Age of Baby Weight of Baby Amount per feeding Feeds per 24 Hours
Birth-1 week 3.0 kg (7 lb) 2-3 fl oz each 6-10
1-4 weeks 3.5 kg (8 lb) 2-4 fl oz each 7–8
1–3 months 4.5 kg (10 lb) 4-5 fl oz each 5–6
3–6 months 5.5 kg (12 lb) 6-7 fl oz each 4–5
6–9 months 6.5 kg (14 lb) 7-8 fl oz each 3–4
9 -12 months 8 kg (18 lb) 7-8 fl oz each 3


This chart is based on bottle formula feeding only. Daily frequency and volume of feeding represent averages based on estimated caloric intake of babies 0 to 12 months.

Additional Feeding Advice:

  • Always measure the water before adding the formula powder.
  • Ensure the water is no more than 30 minutes from boiling before mixing with formula to ensure it’s at a safe temperature.
  • Stir or shake the bottle well to dissolve the powder completely.
  • Test the formula’s temperature on the inside of your wrist before feeding to ensure it’s not too hot.
  • If your baby doesn’t finish a bottle, discard the unused formula and do not reuse it to maintain hygiene.
  • Adjustments to the feeding schedule or amounts may be necessary based on your baby’s growth and appetite changes. Consult a healthcare professional for personalized advice.
  • Transitioning to solid foods usually begins around 6 months of age, but Similac Baby Formula can continue to be an important part of your baby’s diet as you introduce new foods.

Remember, feeding times are also bonding times. Enjoy these moments with your baby. If you have any concerns about your baby’s nutrition or feeding patterns, it’s best to consult a pediatrician.

Storage and Safety Information

  • Store in a cool, dry place before opening.
  • Use opened sachets within 4 weeks.
  • Never use a microwave to warm feeds due to the risk of uneven heating and scalding.


For the latest prices of Similac 360 Total Care Infant Formula in a 30.8 oz can, I recommend checking with major retailers like Amazon, Walmart, Target, and the official Similac website. Prices can vary based on location, current promotions, and whether you’re buying in-store or online. Additionally, signing up for brand newsletters or joining loyalty programs may offer discounts or special deals.

Conclusion Similac 360 Total Care Infant Formula

Similac 360 Total Care Infant Formula stands out for its formulation that mimics breast milk closely, providing essential nutrients for infants’ growth and development. It’s designed with five HMO prebiotics for immune support, brain development, and digestive health, making it a comprehensive choice for infant nutrition. The non-GMO formula without artificial growth hormones appeals to health-conscious parents seeking high-quality options for their babies. Prices vary by retailer, so checking various sources is recommended for the best deal.

As with any infant formula, I recommend consulting a healthcare professional to ensure it meets the specific needs of your baby. However, based on my comprehensive testing and evaluation, Similac 360 Total Care is a product I would recommend to parents seeking an organic formula option. Happy Feeding!

For more detailed information, please visit the Similac 360 Total Care Product Page. They provide in-depth details about their formula range, including ingredients, nutritional benefits, and guidance on selecting the right product for your baby’s needs.

Disclaimer: The content available on Little Baby Formula’s website is intended solely for your general knowledge. Little Baby Formula does not offer medical guidance or participate in medical practices. We recommend consulting your pediatrician before choosing to use bottle-feeding. Results may differ from person to person.
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Hello, I’m Andreas, a 45-year-old father living a life full of joy and challenges in Germany and different countries in Asia (Cambodia, Philippines, Vietnam). Married since 2012, my wife and I have been blessed with four incredible sons who have turned our world into an endless adventure of love, laughter, and discovery. My journey through parenthood, coupled with years of background in pediatric nutrition and the baby formula industry, has shaped me into a trusted voice for parents navigating the complex world of infant feeding. This unique blend of professional knowledge and personal experience has given me an in-depth understanding of the nuances involved in ensuring our little ones receive the best possible nutrition from their earliest days.

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